منابع مشابه
Membrane vesicles shed by oligodendroglioma cells induce neuronal apoptosis.
In order to investigate the mechanism by which oligodendrogliomas cause neuronal damage, media conditioned by G26/24 oligodendroglioma cells, were fractionated into shed vesicles and vesicle-free supernatants, and added to primary cultures of rat fetal cortical neurons. After one night treatment with vesicles, a reproducible, dose-dependent, inhibitory effect on neurite outgrowth was already in...
متن کاملVesicles Azurophil Granules Specific Granules Gelatinase Granules Secretory Vesicles Membrane Membrane Membrane Membrane CD
neity simply that some proteins must be segregated to survive P inside the neutrophil, or for the neutrophil to survive, much OLYMORPHONUCLEAR leukocytes were discovered by Paul Ehrlich, when fixation and staining techniques as two-component glue has to be stored in two separate made it possible to identify the lobulated nucleus and the tubes, although both will be used at the same time? Whethe...
متن کاملApoptosis-inducing factor
Although the seminal paper by Kerr, Wyllie and Currie (Kerr et al., 1972), who coined the word ‘apoptosis’, stated that only nuclei but not cytoplasmic organelles would undergo major modifications in the dying cell, recent evidence suggests that no cellular compartment is spared (Ferri and Kroemer, 2001). Mitochondria are particularly affected early during the apoptotic process, and they are no...
متن کاملbrush-border membrane vesicles
The characteristics of hypoxanthine transport were examined in purified brush-border membrane vesicles isolated from guineapig kidney. Hypoxanthine uptake in the vesicles was specifically stimulated by both Na+ and an inside-negative potential, resulting in a transient accumulation of intravesicular hypoxanthine. Na+-dependent hypoxanthine influx was saturable (apparent Km 4.4 + 2.1 ,uM, Vmax 1...
متن کاملplasma-membrane vesicles
Transport of [14C]tetraethylammonium (TEA), an organic cation, was studied in brush-border (BBMV) and basolateral (BLMV) membrane vesicles isolated from rabbit kidney cortex. In BBMV, the presence of an outwardly directed H+ gradient induced a marked stimulation of TEA uptake against its concentration gradient (overshoot phenomenon), whereas a valinomycin-induced inside-negative potential had n...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2001
ISSN: 0021-9258
DOI: 10.1074/jbc.m107005200